Things to consider as starting points: What is the theoretical basis for the characterization technique, synthetic method and/or general theme? What are the nuts and bolts of the method, e.g. for a characterization technique samples size, geometry, sample prep, etc? What is the current state of the art regarding this topic? For instruments: Who are the leading manufacturers in the field and what is the typical cost of the instrument? For other topics: Who are the leading researchers in the field? What are the limitations associated with the topic? Is there room for improvement?