Because knowledge of human physiology and pathophysiology has grown rapidly over the past 100 years, it is no longer logical to teach each discrete disease process in a single pathophysiology course. Instead, we focus on educating students to identify deviation from normal physiology by identifying themes of alteration that can be applied to various diseases within body function systems so that they will be able to apply principles of pathophysiology to unfamiliar disease processes and infer general mechanisms of disease, appropriate treatment modalities. The final essay in this course will ask you to demonstrate this essential skill. You will also be creating a concept map and a case study as a part of this project.
For your final essay, you will write a 4-8 **CANNOT EXCEED 8 PAGES** page paper examining the pathophysiology of a complex, multi-system disease process.
A complex, multi-system disease process is defined as a condition or disorder that either affects the whole body or involves multiple organs. Your textbook uses diabetes as an example of a complex, multi-system disease process; while fundamentally a disease of dysfunctional glucose regulation, it affects nearly every system in the body and leads to altered elimination, altered perfusion, and so on.
You may select any complex, multi-system disease process that interests you except diabetes–the text has covered this disease in great detail. Some examples of disease process which may be explored include chronic kidney disease, systemic lupus erythematosus, Sjgren’s syndrome, or vasculitis. There are, of course, many other diseases which would be appropriate to explore as nearly every disease process in the human body affects more than one physiologic system. If you have concerns about the appropriateness of your selected disease process, please contact the instructor early in the process of your project to review.
The essay should include four major sections.
1. First, you should describe the altered physiology that leads to the disease state you have chosen. This may include more than one specific alteration.
2. Second, you should describe the clinical manifestations present in the disease, and explain why these manifestations present using pathophysiologic concepts to form your explanation.
3. Third, you should explain how the physiologic alteration causes multi-system alterations in function.
4. Finally, you should describe the treatment modalities used to restore normal function and give a simple explanation as to how the normal function is restored.
Your must follow APA format with appropriate citations